The authors explore the environmental and health impact of persistent chemicals, specifically per- and polyfluoroalkyl substances (PFAS), and compare it to Rachel Carson's 1962 book Silent Spring, which exposed the dangers of DDT and leading to stricter regulations and environmental awareness. Carson’s work stimulated action against harmful chemicals, but PFAS, which were already present in the environment when Carson’s works was writing, went largely unnoticed due to limitations in detection technology at the time. Today, PFAS are ubiquitous and cause harm to ecosystems and human health. Despite regulatory actions like the Stockholm Convention, PFAS emissions and patents have continued to increase, with only a few compounds, such as PFOS and PFOA, being targeted for global restrictions.

The article argues that current chemical regulation is reactive, not precautionary, and suggests that a more proactive approach is needed. With millions of new chemicals being registered annually, many of which may be as persistent as DDT or PFAS. The precautionary principle should be applied to manage these substances, emphasizing the need for chemical innovation focused on sustainability and lifecycle management.

To prevent future harm, the article recommends improving testing methods, developing in silico models for predicting environmental persistence, and enhancing regulatory frameworks that address the entire life cycle of chemicals. This approach will help reduce the accumulation of persistent substances, protect ecosystems, and prevent further environmental crises like the Silent Spring caused by chemical contamination.

The study  “Avoiding the Next Silent Spring: Our Chemical Past, Present, and Future” was published in Environmental Science & Technology